A. He has big eyes and a small nose.

B. She have big eyes and a small nose.

C. She has big eyes and a small nose.

【答案】C

【解析】

A选项意思是：他长着大眼睛和小鼻子 。B选项：have用错，应该用has。C选项是： 她长着大眼睛和小鼻子。C选项正确。故答案为：C。