Hehaslittleacquaintance_______music,whilehehasawideknowledge____painting．
A.with ; ofB.of ; aboutC.with ; aboutD.of ; of在线课程A
解析：
考查短语： have acquaintance with 对什么了解，have a knowledge of 精通，句意：他对音乐不怎么了解，然而他非常精通绘画。故选A。
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